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Third Rock Ventures

Also known as Third Rock

Boston, United States Founded 2007 thirdrockventures.com Boston ecosystem (#4 of 32)

  • Seed
  • Early stage
  • biotech

Third Rock Ventures’s latest fund is Fund VI: $1.1B, 2022, #50 of 427 firms by latest fund.

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Latest fund$1.1B2022
Rank by latest fund#50of 427 firms
Assets under managementNot reported
Funds with reported performance2From public LP disclosures

Overview

Reportedly filed for Fund VII targeting ~$750M; close not confirmed.

Funds

FundClosedSizeSource
Fund VI2022$1.1Bbusinesswire.com

LPs on the record

7 private foundations list on their latest IRS Form 990-PF, and 5 other LPs report holding Third Rock Ventures’s funds.

9 more LPs are in the app. Find LPs that back firms like this one in Hottub’s LP Intelligence: ranked by overlap, with what each holds and how to reach it.

Firms whose LPs overlap

The firms sharing the most LPs on record with Third Rock Ventures, relative to how many LPs each has. A peer set like this is what Find LPs ranks LPs from.

Find LPs for Third Rock Ventures and these firms: Hottub ranks the LPs that hold their funds, the ones still adding funds first.

Track record

A score of 69 out of 100 from the 2 funds public LPs report, 2 of them in the top half of their vintage. Its ranked funds’ median TVPI is 3.04x. Pooled where reports give cash flows: 3.10x TVPI, 3.08x DPI. That ranks it 11th of 123 managers with a score.

Each fund once, as the latest of one LP’s reports ranks it by TVPI against funds of the same vintage in those reports; 50 is the median fund, and a short record is pulled toward 50. The full record in LP Intelligence, with each fund’s rank and what usually follows a fund like its latest, or every manager’s.

Reported fund performance

As reported by public LPs that invested in these funds, net of fees. “Versus vintage” ranks each fund against every other fund of the same vintage in that LP’s report, mostly private equity and venture funds. Open a fund for its cash flows and full peer ranking.

FundVintageNet IRRVersus vintage (IRR)TVPIDPIReported by
Third Rock Ventures III201323.1%Second quartile #2 of 5 2013 funds · median 8.0%2.50x—Alameda County Employees' Retirement Association (ACERA)
Third Rock Ventures II201038.9%Too few peers to rank3.58x—Alameda County Employees' Retirement Association (ACERA)

Alameda County Employees' Retirement Association (ACERA): ACERA Annual Report on Alternative Investments (Government Code Section 7514.7 Disclosures Chart), as of December 31, 2024. From the Alternative Investment Vehicle (AIV) Disclosures Chart that ACERA staff present to the Investment Committee each December under California Government Code Section 7514.7, for the period ending 2024-12-31 (ACERA's fiscal year is the calendar year). The chart says it is prepared by ACERA from its own records and the fund managers' reports and has not been prepared, reviewed or approved by the fund managers. Net IRR is the chart's "Net IRR (Since Inception)" and TVPI its "Investment Multiple (Since Inception)", both as printed; for 36 funds the printed multiple differs from (Cash Distributions + NAV) / Cash Contributions, and DPI is left blank. Amounts are whole US dollars as printed: Commitment, "Cash Contributions (Since Inception)", and "Cash Distributions", which the chart heads "(FY 2024)" on a fiscal-year-end basis and which are cumulative to that date; total value is the printed "Cash Distributions + NAV". Vintage is the chart's "Vintage Year". 3 recent commitments with no NAV yet ("N/A") have only a commitment; 7 funds have no Net IRR ("N/A"), and for 4 more the chart gives a time-weighted return instead of an IRR, which is left blank. The chart lists all 115 alternative investment vehicles together and does not separate asset classes, so besides private equity and venture funds it includes private credit, real estate, infrastructure and other real assets funds; all are included as listed. 46 funds contracted before 2017 are not required to report under Section 7514.7 and are shown where the manager shared the information voluntarily. View source

About this data

Fund sizes come from firm announcements, SEC filings, and press reports, converted to US dollars near the closing date. Compiled as of October 9, 2026. Notable portfolio companies are examples from public sources, not a complete list.

  1. businesswire.com/news/home/20220615005097/en/Third-Rock-V…

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